DSM-5-TR Quick Reference

GENERALIZED ANXIETY DISORDER (F41.1)
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A. Excessive anxiety and worry about multiple events/activities, occurring more days than not for ≥6 months.
B. Difficulty controlling the worry.
C. ≥3 of the following (only 1 required in children):
   1. Restlessness or feeling keyed up/on edge
   2. Easily fatigued
   3. Difficulty concentrating or mind going blank
   4. Irritability
   5. Muscle tension
   6. Sleep disturbance (difficulty falling/staying asleep, or restless sleep)
D. Causes clinically significant distress or functional impairment.
E. Not attributable to substances or another medical condition.
F. Not better explained by another mental disorder.

MAJOR DEPRESSIVE DISORDER, SINGLE EPISODE (F32.x)
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ICD-10: F32.0 mild | F32.1 moderate | F32.2 severe (no psychosis) | F32.3 severe (with psychosis)

A. ≥5 of the following during the same 2-week period; must include (1) or (2):
   1. Depressed mood most of the day, nearly every day
   2. Markedly diminished interest or pleasure in activities (anhedonia)
   3. Significant weight/appetite change (>5% body weight in 1 month)
   4. Insomnia or hypersomnia
   5. Psychomotor agitation or retardation (observable by others)
   6. Fatigue or loss of energy
   7. Feelings of worthlessness or excessive/inappropriate guilt
   8. Diminished ability to think, concentrate, or make decisions
   9. Recurrent thoughts of death, suicidal ideation, or suicide attempt/plan
B. Causes clinically significant distress or functional impairment.
C. Not attributable to substances or another medical condition.
D. Not better explained by schizoaffective, schizophrenia, or psychotic disorders.
E. No history of manic or hypomanic episode.

Specifiers: with anxious distress | with mixed features | with melancholic features | with atypical features | with mood-congruent/incongruent psychotic features | with peripartum onset | with seasonal pattern

MAJOR DEPRESSIVE DISORDER, RECURRENT (F33.x)
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ICD-10: F33.0 mild | F33.1 moderate | F33.2 severe (no psychosis) | F33.3 severe (with psychosis)

Same criteria as MDD Single Episode (Criterion A–E above), PLUS:
- Presence of ≥2 major depressive episodes separated by ≥2 months of remission.

Specifiers: with anxious distress | with mixed features | with melancholic features | with atypical features | with mood-congruent/incongruent psychotic features | with peripartum onset | with seasonal pattern

POSTTRAUMATIC STRESS DISORDER, UNSPECIFIED (F43.10)
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Exposure to actual or threatened death, serious injury, or sexual violence (direct, witnessed, learned of close person, or repeated/extreme indirect exposure).

A. INTRUSION (≥1):
   1. Recurrent, involuntary, intrusive distressing memories
   2. Recurrent distressing dreams
   3. Dissociative reactions (flashbacks)
   4. Intense/prolonged psychological distress at trauma cues
   5. Marked physiological reactions to trauma cues

B. AVOIDANCE (≥1):
   1. Avoidance of distressing trauma-related thoughts/feelings
   2. Avoidance of external reminders (people, places, situations)

C. NEGATIVE COGNITIONS/MOOD (≥2):
   1. Inability to remember important aspects of trauma
   2. Persistent negative beliefs about self, others, or the world
   3. Persistent distorted blame of self or others
   4. Persistent negative emotional states (fear, horror, anger, guilt, shame)
   5. Markedly diminished interest/participation in activities
   6. Feelings of detachment/estrangement from others
   7. Persistent inability to experience positive emotions

D. ALTERATIONS IN AROUSAL/REACTIVITY (≥2):
   1. Irritable behavior/angry outbursts
   2. Reckless or self-destructive behavior
   3. Hypervigilance
   4. Exaggerated startle response
   5. Problems with concentration
   6. Sleep disturbance

Duration: >1 month
Causes clinically significant distress or functional impairment.
Not attributable to substances or another medical condition.

Specifiers: with dissociative symptoms (depersonalization/derealization) | with delayed expression (full criteria not met until ≥6 months after event)

POSTTRAUMATIC STRESS DISORDER, ACUTE (F43.11)
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Duration of symptoms: 1–3 months.

Exposure to actual or threatened death, serious injury, or sexual violence (direct, witnessed, learned of close person, or repeated/extreme indirect exposure).

A. INTRUSION (≥1):
   1. Recurrent, involuntary, intrusive distressing memories
   2. Recurrent distressing dreams
   3. Dissociative reactions (flashbacks)
   4. Intense/prolonged psychological distress at trauma cues
   5. Marked physiological reactions to trauma cues

B. AVOIDANCE (≥1):
   1. Avoidance of distressing trauma-related thoughts/feelings
   2. Avoidance of external reminders (people, places, situations)

C. NEGATIVE COGNITIONS/MOOD (≥2):
   1. Inability to remember important aspects of trauma
   2. Persistent negative beliefs about self, others, or the world
   3. Persistent distorted blame of self or others
   4. Persistent negative emotional states (fear, horror, anger, guilt, shame)
   5. Markedly diminished interest/participation in activities
   6. Feelings of detachment/estrangement from others
   7. Persistent inability to experience positive emotions

D. ALTERATIONS IN AROUSAL/REACTIVITY (≥2):
   1. Irritable behavior/angry outbursts
   2. Reckless or self-destructive behavior
   3. Hypervigilance
   4. Exaggerated startle response
   5. Problems with concentration
   6. Sleep disturbance

Causes clinically significant distress or functional impairment.
Not attributable to substances or another medical condition.

Specifiers: with dissociative symptoms (depersonalization/derealization) | with delayed expression

POSTTRAUMATIC STRESS DISORDER, CHRONIC (F43.12)
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Duration of symptoms: >3 months.

Exposure to actual or threatened death, serious injury, or sexual violence (direct, witnessed, learned of close person, or repeated/extreme indirect exposure).

A. INTRUSION (≥1):
   1. Recurrent, involuntary, intrusive distressing memories
   2. Recurrent distressing dreams
   3. Dissociative reactions (flashbacks)
   4. Intense/prolonged psychological distress at trauma cues
   5. Marked physiological reactions to trauma cues

B. AVOIDANCE (≥1):
   1. Avoidance of distressing trauma-related thoughts/feelings
   2. Avoidance of external reminders (people, places, situations)

C. NEGATIVE COGNITIONS/MOOD (≥2):
   1. Inability to remember important aspects of trauma
   2. Persistent negative beliefs about self, others, or the world
   3. Persistent distorted blame of self or others
   4. Persistent negative emotional states (fear, horror, anger, guilt, shame)
   5. Markedly diminished interest/participation in activities
   6. Feelings of detachment/estrangement from others
   7. Persistent inability to experience positive emotions

D. ALTERATIONS IN AROUSAL/REACTIVITY (≥2):
   1. Irritable behavior/angry outbursts
   2. Reckless or self-destructive behavior
   3. Hypervigilance
   4. Exaggerated startle response
   5. Problems with concentration
   6. Sleep disturbance

Causes clinically significant distress or functional impairment.
Not attributable to substances or another medical condition.

Specifiers: with dissociative symptoms (depersonalization/derealization) | with delayed expression

PTSD WITH DISSOCIATIVE SYMPTOMS (F43.10, with dissociative symptoms specifier)
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Meets full criteria for PTSD (F43.10) PLUS persistent or recurrent:

  Depersonalization: Feeling detached from one's mental processes or body
                     (e.g., feeling as if in a dream, unreality of self)
  OR
  Derealization:     Experiences of unreality of surroundings
                     (e.g., world is dreamlike, distant, distorted)

Not attributable to substances, another medical condition, or psychotic disorder.

ADJUSTMENT DISORDER WITH DEPRESSED MOOD (F43.21)
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A. Emotional/behavioral symptoms in response to an identifiable stressor, within 3 months of stressor onset.
B. Clinically significant:
   - Marked distress out of proportion to the severity/context of the stressor
   - OR significant impairment in social, occupational, or other functioning
C. Does not meet criteria for another mental disorder; not an exacerbation of a preexisting disorder.
D. Symptoms do not represent normal bereavement.
E. Symptoms resolve within 6 months of stressor (or its consequences) terminating.

Predominant presentation: Low mood, tearfulness, feelings of hopelessness.

ADJUSTMENT DISORDER WITH ANXIETY (F43.22)
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A–E: Same criteria as Adjustment Disorder (see above).

Predominant presentation: Nervousness, worry, jitteriness; OR separation anxiety in children.

ADJUSTMENT DISORDER WITH MIXED ANXIETY AND DEPRESSED MOOD (F43.23)
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A–E: Same criteria as Adjustment Disorder (see above).

Predominant presentation: Combination of depression and anxiety symptoms.

ADJUSTMENT DISORDER WITH DISTURBANCE OF CONDUCT (F43.24)
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A–E: Same criteria as Adjustment Disorder (see above).

Predominant presentation: Disturbance of conduct (e.g., fighting, reckless driving, defaulting on legal responsibilities, truancy).

ADJUSTMENT DISORDER WITH MIXED DISTURBANCE OF EMOTIONS AND CONDUCT (F43.25)
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A–E: Same criteria as Adjustment Disorder (see above).

Predominant presentation: Both emotional symptoms (depression, anxiety) AND disturbance of conduct.

ADJUSTMENT DISORDER, UNSPECIFIED (F43.20)
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A–E: Same criteria as Adjustment Disorder (see above).

Predominant presentation: Maladaptive reactions not classifiable as one of the other subtypes (e.g., physical complaints, social withdrawal, work/academic inhibition without significant emotional or conduct disturbance).

ADHD, COMBINED PRESENTATION (F90.2)
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Meets criteria for BOTH Inattention and Hyperactivity-Impulsivity below.

INATTENTION (≥6 symptoms for ≥6 months; ≥5 for age 17+):
   1. Fails to give close attention / makes careless mistakes
   2. Difficulty sustaining attention in tasks or play
   3. Does not seem to listen when spoken to directly
   4. Does not follow through on instructions; fails to finish tasks
   5. Difficulty organizing tasks and activities
   6. Avoids/dislikes tasks requiring sustained mental effort
   7. Loses things necessary for tasks
   8. Easily distracted by extraneous stimuli
   9. Forgetful in daily activities

HYPERACTIVITY-IMPULSIVITY (≥6 symptoms for ≥6 months; ≥5 for age 17+):
   1. Fidgets with or taps hands/feet; squirms in seat
   2. Leaves seat when remaining seated is expected
   3. Runs/climbs in situations where inappropriate (in adults: restlessness)
   4. Unable to engage in leisure activities quietly
   5. "On the go" / acts as if "driven by a motor"
   6. Talks excessively
   7. Blurts out answers before question is complete
   8. Difficulty waiting their turn
   9. Interrupts or intrudes on others

Additional criteria:
- Several symptoms present before age 12
- Symptoms present in ≥2 settings
- Causes significant impairment in social, academic, or occupational functioning
- Not better explained by another mental disorder

Specifiers: mild | moderate | severe | in partial remission

ADHD, PREDOMINANTLY INATTENTIVE PRESENTATION (F90.0)
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Meets criteria for INATTENTION but NOT Hyperactivity-Impulsivity (see ADHD Combined for full symptom lists).

≥6 inattention symptoms for ≥6 months (≥5 for age 17+).
Hyperactivity-impulsivity criteria NOT fully met.

Additional criteria:
- Several symptoms present before age 12
- Symptoms present in ≥2 settings
- Causes significant impairment in social, academic, or occupational functioning
- Not better explained by another mental disorder

Specifiers: mild | moderate | severe | in partial remission

ADHD, PREDOMINANTLY HYPERACTIVE-IMPULSIVE PRESENTATION (F90.1)
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Meets criteria for HYPERACTIVITY-IMPULSIVITY but NOT Inattention (see ADHD Combined for full symptom lists).

≥6 hyperactivity-impulsivity symptoms for ≥6 months (≥5 for age 17+).
Inattention criteria NOT fully met.

Additional criteria:
- Several symptoms present before age 12
- Symptoms present in ≥2 settings
- Causes significant impairment in social, academic, or occupational functioning
- Not better explained by another mental disorder

Specifiers: mild | moderate | severe | in partial remission